Depakote (divalproex sodium), is an anti-convulsant medication used to treat epilepsy and manic episodes in bipolar disorder. Use of Depakote by pregnant women poses the risk of serious Depakote birth defects in their unborn infants including spinal birth defects, malformations of the hands, mid face and ribs, heart defects and malformations of male genitalia including undescended testes. The defects can cause fetal or neonatal death.
Studies of Depakote Birth Defects
A recent study concluded that women who take Depakote during pregnancy have a 12.7 times greater risk of having a child with spina bifida than women who do not take the drug. In spina bifida, the spinal column and backbone fail to fully develop and close creating a risk of infection and often resulting in neurological disabilities.
A seven year study was conducted at five Boston area hospitals and involved more than 1000 patients. The study found that more than 20% of infants born to Depakote mothers had serious birth defects. The rate of birth defects was dosage dependent and women who took less than the recommended dosage of the drug had a 9.1% chance of having an infant with severe birth defects.
The New England Journal of Medicine published a study in April of 2001 which reported that the frequency of major malformations, hypoplasia of the mid face and fingers and growth retardation is increased in babies exposed to anticonvulsant drugs. These specific birth defects are referred to as anticonvulsant embryopathy.
A study published by Neurology in August 2006 recommended that Depakote be a last resort when prescribing anticonvulsants for pregnant women with epilepsy. The study reported that the prevalence of major congenital defects and fetal deaths was significantly higher in women who took Depakote during pregnancy compared to women who took antiepileptic drugs that did not contain valproate sodium.
In addition to serious physical malformations and birth defects, a recent study in Denmark found a 2.8% increased risk for Autism spectral disorder in children whose mothers took Depakote or a generic form of valproate during pregnancy.
Although the primary use for Depakote is to prevent epileptic seizures, it has also been prescribed as a mood stabilizer in the treatment of bipolar disorder and it has been used in treatment of chronic migraine headaches. Women of childbearing age who take Depakote for any reason should be aware of the significant risk of birth defects.
The FDA classifies Depakote as a Class D drug because it is known to cause a significant risk of birth defects when taken by pregnant women. Manufactured by Abbott Pharmaceuticals Ltd., the drug has been on the market since 1983. The ingredient in Depakote that is responsible for most of the risk of fetal injury is valproate sodium which is also sold under generic names by several pharmaceutical companies.
A class action has been filed in the United Kingdom for disabling birth defects attributed to the drug Epilim, another anticonvulsant that contains valproate sodium. Women planning to become pregnant should discuss all their medications with their doctors and find appropriate substitutes for anticonvulsants whenever possible.
A class action lawsuit for Depakote birth defects was filed in St. Clair County Circuit Court in Illinois in March of 2011. More than 2 dozen plaintiffs are party to this action and additional class actions may be filed. Numerous individual lawsuits have been filed in state and federal district courts, but at this time no mass torts or multidistrict litigation (MDL) have been formed.
In a class action, multiple plaintiffs file a single lawsuit for similar injuries, with the same cause of action against the same defendant(s). A class action has a single trial and a single verdict that is divided between the plaintiffs. Mass torts and MDLs are similar individual lawsuits that are consolidated by state or federal courts for discovery and evidentiary purposes in order to expedite the legal process. Each lawsuit is tried individually with the same evidence and testimony established during the mass tort or MDL hearings.
Pending lawsuits include actions brought by parents of children born with birth defects and actions brought by adult children of Depakote users who are still suffering from the effects of birth defects.
Allegations include charges that Abbott Pharmaceuticals knew or should have known about the risks that Depakote posed to pregnant women and that they failed to adequately warn consumers and healthcare professionals of the significant potential for fetal injury. The FDA ordered Abbott to update the label warnings in 2009 after data from the North American Antiepiletic Drug Pregnancy Registry indicated that more than 10% of pregnant women taking Depakote gave birth to infants with birth defects or a physical abnormality linked to the drug.
Legal Help for Victims of Depakote
If you or someone you know took Depakote during pregnancy and gave birth to a child with Depakote birth defects, you can get a free compensation evaluation of your case by completing our short questionnaire. You may be entitled to compensation for medical expenses, lost income and other costs associated with your child’s special needs. Our trained professionals are available to answer your questions and will help you find an attorney to assist you in pursuing legal action for your child’s injuries.
Everything You Need to Know about Filing a Depakote Lawsuit
If you are looking for the necessary details to file a Depakote lawsuit, then keep reading because you’re on the right site. If you are a pregnant woman or a new mom and have been prescribed Depakote treatment, then you probably know its devastating side effects. And, if unfortunately your newborn developed or is developing one of Depakote birth defects, then maybe you should seriously consider filing a Depakote lawsuit. Even though you cannot do much about the Depakote birth defects your child is suffering from, you can definitely fight for his or her right to have a better life.
Depakote Lawsuit :Getting Compensated
But for this, you have to take action quickly and get the information you need in order to be able to file a Depakote lawsuit as soon as possible. In fact, keep in mind the statutes of limitations!
On this website, you’ll find everything you need to know about Depakote’s side effects on grown-ups and unborn babies and even how you can get a Depakote Lawyer. This way, you can easily file a lawsuit against those who are responsible for your painful situation.
Today, we offer you our help by providing you the chance to find out whether you are eligible to receive any compensation or not from the manufacturer of Depakote. If you want to receive our FREE Depakote compensation evaluation form now, then feel free to enter your info above and you’ll receive our online form within minutes via email.
It’s a very short form to fill out. Once submitted, it will be reviewed immediately for FREE and you’ll know within 24 hours if you qualify for Depakote compensation. Then, if you qualify, you’ll be contacted by experienced lawyers and legal experts to help you with your case.
This is a very important stage as it can help you avoid the hassle of filing a lawsuit without having any chances to win. By knowing first your compensation eligibility, you can take the appropriate decision about filling a Depakote lawsuit.
Depakote Lawsuit : Complete Information on Depakote
Depakote is a drug widely used especially to treat depressive disorders such as maniac episodes. Even though it was successfully used for several years, Depakote has always presented some terrible side effects and more precisely birth defects on newborns.
In fact, it was reported that all pregnant women under Depakote treatment seem to be at risk of experiencing birth defects issues. Over the years, Depakote attorneys managed to win many cases which imply various those side effects. Lately, Depakote is not that prescribed anymore, especially to pregnant women.
Unfortunately, for many babies and parents, it is too late. But, if your child suffers because you took Depakote while you were pregnant, you can rely on our support and find out everything you have to know about the eligibility aspects and the procedures of your potential Depakote lawsuit.
Filing a Depakote Lawsuit
If you plan to file a Depakote lawsuit, you should know that you have great chances to get Depakote settlements. The great thing about getting a specialized lawyer is that he can understand you better than anyone else and even more important, he knows how to help you win your Depakote lawsuit.
Even though there is no sum of money which can compensate your child’s suffering, the lawyers can definitely assist you to get the right compensation, which can deliver better treatments to your child.
So, the first step that you should complete is to sign up our free compensation evaluation form. This form furnishes the essential details that will help experienced Depakote lawyers understand your problems and advise you accordingly.
If you meet the eligibility criteria, you can definitely file a Depakote lawsuit as you have great chances to win the trial and obtain the right compensation to cover for all your medical bills and any other costs linked to these defects.
Unfortunately, a large number of individuals have suffered because of surgical mesh complications. They are looking into filing a Mesh Lawsuit to investigate their legal options regarding financial compensation for medical bills and pain and suffering. There is limited time when filing a Mesh Lawsuit, so it is important to seek legal counsel as soon as possible. For a consultation, complete the form and a Mesh Lawsuit attorney will be in touch with you to answer all your legal questions.
You owe it to yourself to speak with a Mesh attorney regarding numerous potential surgical mesh side effects and symptoms. Side effects may include infections, bleeding, abdominal pain, mesh erosion, or other unusual abdominal symptoms. If you or a loved one has suffered adverse side effects connected to mesh surgery, a Mesh Lawsuit attorney can help you understand your legal options and whether you are entitled to financial compensation for your medical bills and pain and suffering. No matter what type or brand of surgical mesh implant you received, if it was defective or caused unusual pain or injury, you may be among the individuals eligible for a Mesh Lawsuit.
Patients suffering from complications following a surgical mesh implant may need to consider a filing a Mesh Lawsuit. There are numerous types of surgical mesh implants on the market. Most recently, transvaginal surgical mesh products have been the subject of Mesh Lawsuits. If you were injured by a vaginal mesh product and would like to be connected with a Mesh Lawsuit attorney, please fill out the form.
Avaulta Mesh Injuries Cause Lawsuits
Vaginal mesh devices like Avaulta, manufactured by C.R. Bard, were intended to help women suffering from weakened vaginal muscles.
Why Did Avaulta Vaginal Mesh Fail So Many Women?
Vaginal mesh surgery involved implanting the device through an incision in the vaginal wall, to help hold pelvic organs in their proper places. Devices like Avaulta turned out to be poorly designed, and caused women to experience injuries including organ perforation, internal bleeding, nerve damage, and chronic pain, because it turns out that in addition to questionable design, the mesh devices are highly incompatible with the pelvic region of a woman’s body.
In an effort to get relief from their suffering, many women have undergone multiple surgeries to remove the vaginal mesh devices from their bodies, only to discover that the device cannot be completely removed, causing permanent injuries. Further surgical complications have actually worsened symptoms for a large number of these women, causing the original incontinence or organ prolapse to become worse than it was before the initial surgical procedure.
As a result, women have chosen to exercise their legal rights by filing lawsuits against various medical device manufacturers that developed and sold vaginal mesh products. These devices were not thoroughly tested, and were approved by the U.S. Food and Drug Administration through a loophole known as 510(k), which allows medical devices deemed “substantially similar” to existing devices to bypass critical testing, including clinical trials on human subjects. To date, there have been several high-profile vaginal mesh trial verdicts in favor of plaintiffs, which have resulted in significant compensatory damages for medical expenses, as well as extensive pain and suffering.
Take Control of Your Health and Speak to a Physician About Avaulta Failure Symptoms
Contending with stress urinary incontinence and pelvic organ prolapse is difficult, especially when a procedure as highly touted as vaginal mesh surgery does not accomplish what it promised to do.
If you have undergone vaginal mesh surgery and your symptoms have not gotten better, it is important to contact your physician immediately. The sooner vaginal mesh failure is addressed, the more likely you will be able to minimize the degree of injury you experience. Moreover, if you feel you have grounds to sue C.R. Bard for the injuries you’ve suffered as a result of implantation of an Avaulta vaginal mesh device, you should contact an experienced personal injury lawyer to help you through the process.
A Mesh Lawsuit should be considered if you experience unexplained abdominal pain, fever, or tenderness due to a surgical mesh implant. You owe it to yourself to speak with a lawyer regarding a Mesh Lawsuit. Many types of Surgical Mesh products have been common targets in the history of Mesh Lawsuits. Defective vaginal surgical mesh products can also injure a woman’s partner during sexual intercourse. In this case, both the woman and the other injured party are potentially eligible to file a Mesh Lawsuit.
Mesh Lawsuit is a broad term used to reference lawsuits that are filed against the makers of the surgical mesh patches. The term Mesh Lawsuit is not associated with any particular brand of surgical mesh implants. Regardless of what brand or type of surgical mesh implants you had implanted, if the mesh implant was defective and caused you pain or injury you may be eligible for a Mesh Lawsuit. Fill out the form to be put in touch with a lawyer that can speak to you about your potential Mesh Lawsuit.
Lawsuits have a limited amount of time to be filed. Please consider filling out the form to the right with the proper information and we will have an experienced lawyer contact you in reference to your personal Mesh Lawsuit. You may be entitled to compensation for any injuries sustained due to a surgical mesh implant. The time is now. Fill this form today to take the first step.
Transvaginal Mesh Defects & Lawsuits – Cases
You may be entitled to compensation!
Transvaginal Mesh Claims – Lawsuits – Recall Information
In the 1990’s the use of surgical mesh became common in transvaginal repair procedures for pelvic organ prolapsed and stress urinary incontinence.
It was thought that the procedure offered a minimally invasive alternative for traditional surgeries. Recent research from the FDA shows that these procedures may have serious side effects for patients such as mesh erosion, additional surgeries (revision surgeries), pain sometimes very serious pain – , and even death.
VAGINAL MESH: WHAT YOU NEED TO KNOW
Pelvic Organ Prolapse (POP) occurs when the muscles and tissues around the pelvic organs stretch and – or weaken. This then can cause the organs to bulge into the vaginal wall.
Stress Urinary Incontinence (SUI) takes place when there is a leakage of urine during times of physical activity. This can include relatively simple activities such as sneezing, coughing, laughing, or light exercise, not to mention more strenuous forms of exercise.
Vaginal mesh products are one item used to treat SUI and POP.
The FDA first cleared a product for surgical mesh treatment of SUI in 1996.
The FDA cleared the first mesh product for POP procedures in 2002.
In SUI repairs, the mesh is used as a sling device to support the urethra.
About 80% of SUI repairs was made with mesh products.
Sadly for many patients, in both 2011 and 2008 the FDA warned of the adverse side effects of implanted mesh products.
At the time of writing this, the FDA get in excess of 3,850 reports from patients of death, malfunction, and injury due to transvaginal mesh procedures.
Due to the serious nature of these injuries, we encourage patients who have suffered with these devices to contact our lawyers as soon as possible.
One of the main complications of these devices includes erosion. This is also sometimes known as exposure, extrusion, and – or protrusion of the device.
Other symptoms of complications include, but are not limited to, dyspareunia, infection, pain, urinary problems, organ perforation, and bleeding.
There are also reports of incontinence, prolapse, vaginal scarring, neuro-muscular damage and problems, vaginal shrinkage, and emotional problems such as depression. Many of these issues often require hospitalization and more revision surgeries. Some women have had to have even more than a dozen revision surgeries.
Various Examples of Side Effects of Transvaginal Mesh Products Include Potentially:
- Vaginal shortening and – or shrinking; Infection; Bleeding; Erosion through the vagina; Organ perforation of the bowel, blood vessel, or bladder; Additional revision surgeries; Painful sexual intercourse (dyspareunia); Severe pelvic vaginal pain; Inability to engage in sexual intercourse; Neuro-muscular issues; Recurrence of prolapse and – or incontinence; Vaginal scarring; Mesh contraction
Types of Transvaginal Mesh
In general, mesh product materials can be sorted into four types:
- Absorbable synthetic materials · Biological materials such as acellular collagen derived from porcine or bovine sources · Non-absorbable synthetic materials such as polyester and – or polypropylene · Composites that can include mixes of any of the above three types
Who are Synthetic Mesh Manufacturers?
The FDA has identified some of the manufacturers mentioned in reports of post-surgical transvaginal mesh complications, and these include:
– Johnson & Johnson; Boston Scientific Corp.; Cook; American Medical Systems; Covidien; CR Bard
Additionally, complaints have been made about products manufacturered by General Medical Devices, Ethicon, Inc., Caldera Medical, and Endo Pharmaceuticals.
What Type of Transvaginal Mesh Products Have Been Sold in the United States?
Some of the manufacturers and sellers of transvaginal mesh products include Mentor Worldwide, LLC, C.R. Bard, Inc., American Medical Systems, Johnson & Johnson (and J&J’s subsidiary, Ethicon, Inc.), Boston Scientific Corp., and Covidien PLC (including subsidiaries Tyco Healthcare, Sofradim Production, and Tissue Science Laboratories).
C.R. Bard, Inc. transvaginal mesh products (many of which are designed and – or created by a subsidiary of Covidien PLC) include, but may not be limited to:
- Avaulta BioSynthetic Support System; Avaulta Plus BioSynthetic Support System; Avaulta Solo Synthetic Support System; Align; Perfix Plug; Uretex; Pelvilace; Pelvisoft; Pelvicol; Pelvitex
American Medical Systems transvaginal mesh products include: Apogee, Perigee, Monarc, MiniArc, IN-Fast, BioArc, Elevate, Sparc.
Transvaginal mesh products designed and – or manufactured by Tyco Healthcare include: IVS-02, IVS Tunneller – Surgipro.
Boston Scientific Transvaginal Mesh products include: Pinnacle, Uphold, Solyx, Prefyx, Lynx, Obtryx, Advantage, Advantage Fit.
Johnson & Johnson through Ethicon, Inc. transvaginal meshes: Prosima, Gynemesh, Gynemesh PS, Prolift, Prolift M, TVT, TVT-O, TVT Exact, TVT Secur, TVT Abbrevo, TVT Retropubic System.
If you believe that you or a loved one is suffering from complications from a transvaginal mesh product, including any Bard product or Avaulta product, call us today for a free claim evaluation. We have women intake professionals trained to help with your issue that will return your contact.
Do not delay, as your rights and potential compensation may be lost forever if you wait.
Wikipedia often has helpful information about medical devices, drugs, their manufacturers, and side effects of drugs and various medical devices. For example, here is the information available from the Wikipedia website as of March, 2013 concerning Female Genital Prolapse. It is important to remember that the Wikipedia website is written by volunteers, so one should always check with The FDA for accurate and up to date information. In addition, verify the sources cited in any Wikipedia articles for any information of importance.
Never stop taking any medication unless advised to do so by your licensed physician. Information on this website is for general informational purposes only. Always check with your physician before making any health-related decisions regarding your medication, etc.
Wikipedia article as of March, 2013, on Female Genital Prolapse (http://en.wikipedia.org/wiki/Female_genital_prolapse)